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CannaLife Presents, The MISFIT Manifesto: Stop Over-using the Term Synthetic Cannabinoid

  • Writer: Jessica Humphreys
    Jessica Humphreys
  • 6 days ago
  • 4 min read

Updated: 3 hours ago

Because Consumers Deserve Better Than Lazy Labels.


The MISFIT Manifesto

Because Consumers Deserve Better Than Lazy Labels.


Somewhere along the way, cannabis education decided that accuracy was optional.

Apparently, if a compound has anything to do with cannabinoids, we're supposed to throw it into one giant bucket, label it "synthetic," and move on.


Problem solved.

Except it isn't.


When people lump FDA-approved cannabinoid medicines, illicit synthetic cannabinoids like Spice and K2, and chemically converted hemp products into the same conversation, they aren't making science easier to understand.


They're making it harder. And more dangerous.


And when consumers are confused, they don't make better decisions.


They make guesses.


We Have a Vocabulary Problem

The cannabis industry has become comfortable using words that sound meaningful but often aren't.


Natural.

Synthetic.

Medical.

Organic.

Clean.

Plant-based.


These words might be useful in some conversations.

By themselves, they explain almost nothing.


One of the biggest offenders is the phrase "synthetic cannabinoid."

People use it as if it describes one thing.


It doesn't.


It describes a wide range of compounds with very different origins, very different purposes, very different safety profiles and very different levels of scientific evidence.


These differences matter.


Your Body Already Makes Cannabinoids

Here's something that surprises a lot of people.


Long before anyone smoked cannabis, your body was already making cannabinoids. Your endocannabinoid system is a real biological signaling network that helps regulate internal balance, also known as homeostasis.


Among the best-known endocannabinoids are:

  • Anandamide (AEA)

  • 2-AG


Together with cannabinoid receptors and specialized enzymes, these compounds help regulate signaling involved in pain, mood, appetite, stress response, inflammation, memory and many other physiological functions.


This isn't cannabis advocacy.


It's biology.


Not All Cannabinoids Belong in the Same Conversation

One of the easiest ways to reduce confusion is to stop treating every cannabinoid like it's part of the same story.

I will teach four broad categories.


Endocannabinoids

These are made naturally by your own body.

Examples include Anandamide (AEA) and 2-AG.

This is normal human physiology.


Phytocannabinoids

These come from plants.

Cannabis contains well-known compounds including THC, CBD, CBG, CBN, THCV, CBDA and CBGA.

Other plants also produce compounds capable of interacting with cannabinoid pathways.

Nature has been doing interesting chemistry long before humans got involved.


Pharmaceutical Cannabinoids

This is where conversations often fall apart.

Some pharmaceutical cannabinoids are synthesized.

That does not make them the same as illicit synthetic cannabinoids.


FDA-approved cannabinoid medicines are developed under pharmaceutical standards involving:

  • Controlled manufacturing

  • Clinical trials

  • Quality testing

  • Known dosing

  • Regulatory oversight

  • Ongoing safety monitoring


Examples include Marinol®, Syndros® and Cesamet®.


Epidiolex® is different again because it is a purified, plant-derived cannabidiol medicine approved through the FDA drug approval process.


Different origin.

Different evidence.

Different purpose.

Different conversation.


Non-Pharmaceutical Synthetic and Converted Cannabinoids

This is where lots of caution belongs. Products such as Spice and K2 were never designed for consumer use. Many were developed for laboratory research before finding their way into illicit markets.


Then there is deleta-8 THC.


Naturally occurring delta-8 THC exists in cannabis only in very small amounts. This means the vast majority of commercial delta-8 products are not extracted directly from the plant. They are manufactured by chemically converting CBD through a series of chemical reactions.


This is an important distinction.


The problem isn't that chemistry was used.

The problem is what happens during and after the chemistry.


Depending on how a product is manufactured, the final material may contain residual reagents, unknown reaction by-products, contaminants or compounds that were never intended to be consumed.


Many products have entered the marketplace with little meaningful oversight, inconsistent testing and labeling that tells consumers almost nothing about what is actually in the package.


Consumers shouldn't have to wonder:

  • What chemicals were used to make this?

  • Were they completely removed?

  • What reaction by-products remain?

  • Has this batch been independently tested?

  • Does the certificate of analysis even look for the compounds that matter?


Those aren't unreasonable questions.


They're the minimum questions consumers should be asking before inhaling or ingesting any manufactured cannabinoid product.


One Word Doesn't Tell the Whole Story

Imagine walking into a pharmacy and hearing someone say,

"Drugs are dangerous."

Which drugs?

Insulin?

Morphine?

Ibuprofen?

Chemotherapy?


Without context, the statement doesn't tell you much.


The same thing happens when someone says,

"Synthetic cannabinoids are dangerous."

Which ones?

A prescription medication?

An illicit research chemical?

A chemically converted hemp product?


Those are completely different conversations.


If we refuse to make those distinctions, we aren't educating people.

We're oversimplifying the conversation until it stops being useful.


Consumers Deserve Better

This article is about encouraging better conversations becasue consumers deserve clear explanations.


Not catchy headlines.

Not misleading labels.

Not fear.

Not hype.


The cannabis industry has matured enough that we should be capable of having more honest, more accurate discussions. Sometimes the right answer takes another paragraph.


That's okay. Consumers are smarter than many people give them credit for.


The Bottom Line

Science doesn't have to be simplified until it loses its meaning.

It needs to be explained well.


That's the job.


When we use accurate language, consumers make better decisions.

Budtenders give better guidance.

Healthcare professionals have better conversations.


And the entire industry becomes more trustworthy.


That's worth the extra effort.


Welcome to the MISFITS.

I don't expect you'll agree with everything you read here.

But I do expect you'll think about it.


That's enough.


If this article made you think...


Share it.

Quote it.

Debate it.

Teach it.

Email it.

Text it to someone who needs to read it.

If you found value here, help someone else find it too.


Please keep my name attached and link back to the original article whenever you share it.


Because good ideas don't belong in echo chambers.


They belong in conversations.


Jessica Humphreys, BSN

Founder | CannaLife® | CannaLife MISFITS™ | MC Jazzi O™ | CannaLife Press™ | CannaRx™




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